Click on the Auto-Responders link
in the Mail Menu area.
Click on the
delete button 
next to the auto-responder that you want to delete.
Delete an auto-responder when you no longer need to use it. If you use the auto-responder at frequent intervals, such as an "Out of Office" message, you can modify it to point to a nonexistent email account, such as store@yourdomain.com, and then simply change the account name back when you need it again. Refer to Editing an auto-responder for more information.
To delete an auto-responder:
Click on the Auto-Responders link
in the Mail Menu area.
Click on the
delete button next to the auto-responder that you want to delete.